HPLC Column, Diamond Hydride, 4 um, 2.1 mm ID x 50 mm Length, 100 A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 70000‑05P‑2 Diamond Hydride HPLC Column is a short‑bed, narrow‑bore HILIC column designed for fast separations, rapid equilibration, and efficient LC‑MS performance. This configuration is especially well suited for laboratories prioritizing high throughput and reduced analysis time without sacrificing selectivity for polar compounds.
Fast, Efficient HILIC Performance
The 50 mm column length delivers:
Shorter run times
Faster equilibration between injections
Reduced overall method cycle time
The 2.1 mm internal diameter supports lower flow rates, making this column a natural fit for LC‑MS and LC‑MS/MS applications, where solvent load and ionization efficiency are important considerations.
Diamond Hydride™ Stationary Phase Benefits
Built on Cogent TYPE‑C™ silica hydride technology, this Diamond Hydride column offers:
Excellent selectivity for polar and moderately polar analytes
Improved equilibration speed compared to conventional HILIC phases
Robust column lifetime, even under demanding mobile phase conditions
The silica hydride surface provides more stable retention behavior and helps minimize issues commonly associated with traditional bonded silica HILIC phases.
This column is well suited for:
Polar and non‑polar peptides
Amino acids
Metabolites and small biomolecules
Challenging polar compounds analyzed via HILIC
LC‑MS‑Friendly Design
The narrow‑bore format reduces solvent flow into the mass spectrometer, supporting:
Improved electrospray efficiency
Lower solvent consumption
Reduced source contamination
Because of its short length and efficient particle size, this column is a popular choice for screening methods, method development, and high‑throughput LC‑MS assays.
Practical Operation
Despite its extended length and enhanced resolving power, the 70000‑05P‑2 delivers near‑UHPLC separation efficiency without requiring UHPLC‑rated pressures, making it a practical choice for laboratories seeking high resolution with existing instrumentation.
2.1 mm ID column system requirements:
Typical operating flow rates: ~0.2–0.3 mL/min
Requires an HPLC system capable of accurate, stable low‑flow delivery.
Not all standard HPLC pumps are suitable for reliable operation at these flow rates.